Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Spirito, P. et al. It is commonly asymmetrical … Heart 2010; 96(20):1669-75 [8] Richard P, Charron P, ... | PowerPoint PPT presentation | free to view, Global Hypertrophic Cardiomyopathy (HCM) Therapeutics Market Insight and Forecast to 2026. No public clipboards found for this slide. TM, 54, WAS ADMITTED to the ED after a syncopal episode that resulted in a head injury. Hypertrophic cardiomyopathy (HCM) is a condition in which the heart becomes thickened without an obvious cause. Over the years, classification of this condition has been updated by the rapid advancement of genetic, imaging, and clinical investigation. It was first brought to attention by the British forensic pathologist Donald Teare in 1958 as a disease manifesting with symmetric or asymmetric left ventricular hypertrophy (LVH) > 1.5 cm (Figure 23–1) in a nondilated ventricle. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Hypertrophic cardiomyopathy (HCM) is defined by the presence of increased left ventricular (LV) wall thickness (for adults, >15 mm in one or more LV myocardial segments) that is not solely explained by abnormal loading conditions (eg hypertension). Hypertrophic cardiomyopathy (HCM) is a genetic disorder of cardiac myocytes that is characterized by cardiac hypertrophy, unexplained by the loading conditions; a nondilated left ventricle; and a normal or increased ejection fraction. Hypertrophic Cardiomyopathy. In other instances, the cause is unknown. In 2010, the Study Group on peripartum cardiomyopathy of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) defined PPCM as an idiopathic cardiomyopathy occurring towards the end of pregnancy or in the months following delivery, abortion or miscarriage, without other causes for heart failure, and with a left ventricular (LV) ejection fraction (EF) < 45% 5 (see Box). Causes of hypertrophic cardiomyopathy. Retrospective trial by a group at the Mayo Clinic Aim: Long-term effects of myectomy on survival Looked at mortality retrospectively among 3 groups from 1983-2001: 1) myectomy 2) LVOT obstruction w/o surgery 3) Non-obstructive HCM Mean follow-up: 6 yrs Compared to non-operative obstructive, myectomy patients had superior survival free from all-cause mortality / HCM-related mortality / sudden cardiac death. The two patients thought to be in cardiogenic shock were given inotropes … Atrial fibrillation (AF) is frequently associated with HCM with a reported prevalence of about 20% to 25%. MAIN TYPES OF CARDIOMYOPATHY Hypertrophic Cardiomyopathy: Hypertrophy means ‘increase in size.’ It is the increase in size of the heart muscle. This scarring leads to progressive thinning of the septum  outflow tract enlargement (mimicking LV remodeling that occurs after myectomy). Cardiomyopathy Medication Market-Global Forecast to 2025. the diagnosis, characterize the pathophysiology for the individual, and identify risk markers that may inform decisions regarding interventions ... *HCM indicates hypertrophic cardiomyopathy . What Causes Hypertrophic Cardiomyopathy? The main pathophysiology behind is that every organ is in homeostasis with physiological stress. HCM, which occurs in 0.2% of the general population, is the most common cause of sudden cardiac death in young people. In 2010, the Study Group on peripartum cardiomyopathy of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) defined PPCM as an idiopathic cardiomyopathy occurring towards the end of pregnancy or in the months following delivery, abortion or miscarriage, without other causes for heart failure, and with a left ventricular (LV) ejection fraction (EF) < 45% 5 (see Box). INTRODUCTION. Introduction. Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disorder, representing a leading cause of sudden cardiac death in the young and a prevalent cause of heart failure and stroke. You can change your ad preferences anytime. HCM can run in families, but the condition may also be acquired as a part of aging or high blood pressure. Hypertrophic cardiomyopathy. - Title: PowerPoint Presentation Author: Scott Johnson Last modified by: Authorised User Created Date: 3/10/2009 8:02:56 PM Document presentation format, Cardiomyopathy : Causes, Symptoms,Types, Diagnosis and Treatment (1). Classification and Definitions of Cardiomyopathies 9 3.1. 22: Figure 1. Cardiomyopathy is any structural and functional abnormality of the heart muscle unattributable to specific causes or disease processes such as coronary artery disease (CAD), congenital heart disease, or valvular disease. - The report provides comprehensive information on the therapeutics under development for Hypertrophic Cardiomyopathy, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. Etiology of Hypertrophic Cardiomyopathy is mostly due to: - 1. And they’re ready for you to use in your PowerPoint presentations the moment you need them. Pathophysiology MAIN TYPES OF CARDIOMYOPATHY Hypertrophic Cardiomyopathy: Hypertrophy means ‘increase in size.’ It is the increase in size of the heart muscle. Early Detection of Hypertrophic Cardiomyopathy, - Title: Slide 1 Author: mwiegand Last modified by: June Hanks Created Date: 4/15/2008 10:37:56 PM Document presentation format: On-screen Show (4:3) Company. INTRODUCTION. The main pathophysiology behind is that every organ is in homeostasis with physiological stress. Images. 1. In: Kodama K, Haze, K, Hon M, editors. Evaluation and Testing for HCM. Hypertrophic cardiomyopathy (HCM) has been defined morphologically by unexplained hypertrophy in the absence of haemodynamic stress, and at the histological level by myocyte disarray, fibrosis, and abnormalities of the intramyocardial small vessels. Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. These proteins, namely beta-myosin heavy chain, myosin-binding protein C and cardiac troponin C, are structurally important in cardiac muscle. It is commonly asymmetrical with the most severe hypertrophy involving the basal interventricular septum. Causes of sudden cardiac death in young people Myocarditis 3% Maron BJ et al. Hypertrophic cardiomyopathy (HCM) is a condition in which the heart becomes thickened without an obvious cause. the diagnosis, characterize the pathophysiology for the individual, and identify risk markers that may inform decisions regarding interventions ... *HCM indicates hypertrophic cardiomyopathy . 22: Figure 1. When this happens, the ventricle has to work harder to pump out blood. Hypertrophic Cardiomyopathy Dr. Fuad Farooq Resident CardiologyAga Khan University Hospital 2. presentations for free. Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic heart muscle disease affecting 1 of every 500 persons (1, 2).Individuals with HCM are at an increased risk of heart failure and sudden cardiac death ().Usually, HCM is characterized by cardiac hypertrophy with preserved or increased ejection fraction (EF) and cardiac contractility in the absence of secondary causes. Hypertrophic cardiomyopathy. Caused by blockages in coronary arteries ... Mimics myocardial infarction ... Alpha and beta blockers the best treatment. 14. - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Hypertrophic cardiomyopathy is inherited as an autosomal dominant trait and is attributed to mutations in one of a number of genes that encode for one of the sarcomere proteins including beta-cardiac myosin heavy chain (the first gene identified), cardiac actin, cardiac troponin T, alpha-tropomyosin, cardiac troponin I, cardiac myosin-binding protein C, and the myosin light chains. Primary cardiomyopathies 3.1.1 Genetic 3.1.1.1 Hypertrophic cardiomyopathy HCM is a condition of the heart in which a part of the myocardium or the muscle of the Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Do you have PowerPoint slides to share? The disease has complex symptomatology and potentially devastating consequences for … - Famous for being leading cause of sudden cardiac death in young athletes ... Enlarged septum narrows left ventricle outflow tract. Circulation. Change in stress leads to adaptations. 2020 ACC/AHA Guideline for the Diagnosis and Treatment of Patients with Hypertrophic Cardiomyopathy. The parts of the heart most commonly affected are the interventricular septum and the ventricles. Cardiomyopathy: Pathophysiology and Assessment RobertoMLang,MD Circ J 2004; 68: 77-81 Japanese word for octopus catcher Tako-Tsubo Cardiomyopathy Broken Heart Syndrome Apical Balooning 1. HYPERTROPHIC. - Hypertrophic Cardiomyopathy (HCM) Therapeutics market report provides a brief and detailed knowledge of key reports, market conditions and circumstances. - Hypertrophic cardiomyopathy Frank and Mehta Non-Surgical Septal Ablation Echocardiographic still frames (systole) from the parasternal long-axis. Dilated cardiomyopathy is the most common type of cardiomyopathy.Although most cases are idiopathic, a number of conditions (e.g., coronary artery disease, wet beriberi), infections … Sato H, TateishiH, Uchida T, et al. Over the years, classification of this condition has been updated by the rapid advancement of genetic, imaging, and clinical investigation. Hypertrophic cardiomyopathy (HCM) is a genetically determined heart muscle disease most often (60 to 70 percent) caused by mutations in one of several sarcomere genes which encode components of the contractile apparatus of the heart. Powerpoint slides. Circulation. Through a distal port on the balloon-tipped catheter,1-3 mL of ethanol is injected into the septal artery resulting in a controlled myocardial infarction. Hypertrophic Cardiomyopathy Dr. Fuad Farooq Resident CardiologyAga Khan University Hospital. It is occasionally restricted to other myocardial regions, such as the apex, the midportion, and the posterior wall of the left ventricle… N Engl J Med 1997336775-785. However, unlike the type above, the thickened area causes an obstruction that affects the flow of blood leaving the heart. Luis Fuentes V, Wilkie L J (2017) Asymptomative hypertrophic cardiomyopathy: Diagnosis and therapy. The Global Therapeutic Landscape of Hypertrophic Cardiomyopathy - The report provides comprehensive information on the therapeutics under development for Hypertrophic Cardiomyopathy, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. Hypertrophic cardiomyopathy is characterised by the presence of an asymmetrical increase in left ventricular wall thickness, not solely explained by abnormal loading conditions (commonly hypertension and aortic stenosis). Many of them are also animated. If you continue browsing the site, you agree to the use of cookies on this website. HCM can run in families, but the condition may also be acquired as a part of aging or high blood pressure. Change in stress leads to adaptations. 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